1. Destitute or deprived of inhabitants; desert; uninhabited; denoting either stripped of inhabitants, or never having been inhabitated; as a desolate isle; a desolate wilderness.

I will make the cities of Judah desolate, without an inhabitant. Jer 9.

2. Laid waste; in a ruinous condition; neglected; destroyed; as desolate altars; desolate towers. Ezek. Zeph.

3. Solitary; without a companion; afflicted.

Tamar remained desolate in Absaloms house. 2 Sam 13.

4. Deserted of God; deprived of comfort.

My heart within me is desolate. Psa 143.