1. The quality of being an enemy; the opposite of friendship; ill will; hatred; unfriendly dispositions; malevolence. It expresses more than aversion and less than malice,and differs from displeasure in denoting a fixed or rooted hatred, whereas displeasure is more transient.

I will put enmity between thee and the woman. Gen 3.

The carnal mind is enmity against God.Rom 8.

2. A state of opposition.

The friendship of the world is enmity with God. James 4.